It is with an abundance of love and sadness that we announce the passing of Eugene G. Isidro on February 20, 2022 at age 91. Born in the Philippines on June 2, 1930, he was a son of the late Jose and Martina Isidro. He was preceded in death by five brothers – Felipe, Godofredo, Marcellino, Gregorio and Johnny, and his sister, Rosalina Acosta. Dr. Isidro was a 1956 graduate of Santo Tomas University Medical School, Manila, Philippines. He traveled to the U.S. after his internship and chose to study Pathology at Youngstown Hospital Association in Ohio. American citizenship was soon proudly embraced. In 1963, he traveled to Jameson Hospital in New Castle to fill in for the vacationing pathologist. He was warmly received and soon hired as Associate Pathologist. He was the first foreign medical graduate on staff. Dr. Isidro's emergence in the area served as a groundbreaking role, which in turn, through his knowledge, skills and demeanor, quite possibly lead the way for more foreign doctors to join the local community. His association with Jameson lasted 35 years, and he was named Chief Pathologist and Director of Laboratory in 1974. Dr. Isidro was a member of Holy Spirit Parish, St. Camillus. He was an avid golfer and enjoyed bowling. His culinary talents creating delicious eggrolls were always enjoyed during his many holiday parties which he hosted for his staff. One source of pride for Dr. Isidro was the vacation home he built in Royal Palm Beach, FL. Here, he spent many relaxing hours golfing and making family memories. Known as Gene or Geno to close friends and colleagues, he was a loving and devoted family man and friend, known to all for his kindness, intelligence and giving heart. Dr. Isidro is survived by his loving wife of 64 years, Frances (Rega) Isidro; three daughters – Aileen (Jeffrey) Solomon of Moon Township, PA, Lisa Isidro of Cape Coral, FL and Amy Isidro of Vashon Island, WA; and one son – Greg (Joanne) Isidro of Lake Worth, FL. He will also be immensely missed by his grandchildren: Kristin (Ryan) Quartuccio of Cape Coral, FL; Tyler (Rebecca) Larko of Beaver, PA; Alexa (Mark) Savini of Aliquippa, PA; Cody Larko of Cranberry, PA.; Nicholas Isidro of Lake Worth, FL and Charles Leahey of Vashon, WA. Missing their Papa's love and smile are his great-grandchildren, Sophia Quartuccio, Milan Quartuccio, Kingston Quartuccio, Aubrielle Larko, Finn Larko and Emma Larko. Dr. Isidro leaves behind a brother, Jose Isidro of Flushing, NY and many nieces and nephews. The family wishes to thank the staff at Avalon Place and Three Rivers Hospice for their care. In lieu of flowers, the family requests a donation to the City Rescue Mission. Visitation will be held on Tuesday, February 22th from 4:00 – 6:00 PM at the R. Cunningham Funeral Home & Crematory, Inc., 2429 Wilmington Road, New Castle. On Wednesday, February 23rd at 10:30 AM, a funeral procession will leave the funeral home to proceed to St. Camillus Church, 314 W. Englewood Ave., New Castle, where a mass of Christian burial will take place at 11:00 AM. Entombment will take place at Castleview Memorial Gardens.